Título: Breaking Through: My Life in Science
Autor: Katalin Karikó
Sinopse: A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines
“Katalin Karikó’s story is an inspiration.”—Bill Gates
“Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry
A KIRKUS REVIEWS BEST BOOK OF THE YEAR
Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.
Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.
Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.
Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.
Contexto da obra
Como livro em inglês, esta obra costuma ganhar também uma camada própria de interesse editorial e linguístico. “Breaking Through: My Life in Science”, de Katalin Karikó, publicado pela editora Crown, em 2024 e com 336 páginas, integra a categoria Livros em Inglês. Por isso, o interesse da obra tende a se ampliar quando o leitor considera também a relação com a língua em que ela circula.
Editora: Crown
Páginas: 336
Ano: 2024-10-08
Edição:
Linguagem: en
ISBN: 0593443187
ISBN13: 9780593443187
Sobre a editora
Os livros da editora CROWN apresentam uma leitura que mescla narrativas pessoais intensas e relatos investigativos, frequentemente ancorados em histórias reais ou contextos sociais complexos. O catálogo traz obras que exploram desde conflitos culturais profundos, como a vida de mulheres em sociedades restritivas, até análises detalhadas de crises contemporâneas, como ameaças à infraestrutura e desafios políticos. O tom varia entre o rigor documental e o relato íntimo, criando uma experiência que tanto informa quanto provoca reflexão. Muitas obras privilegiam personagens multifacetados e dilemas morais, enquanto outras adotam ritmo mais dinâmico e envolvente, com foco em eventos históricos ou biográficos.
